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Themed collection Coronavirus articles - free to access collection

156 items - Showing page 1 of 3
Editorial

Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research

教育部表示:“那些严重破坏考试秩序,损害教育公平公正的人将得到他们应得的惩罚。”
出境旅游超过1.2亿人次;

Graphical abstract: Editorial Perspectives: will SARS-CoV-2 reset public health requirements in the water industry? Integrating lessons of the past and emerging research
Editorial

Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?

Good luck, good health, hood cheer. I wish you a happy New Year.
娱乐时尚:性感林赛罗韩大"血拼"

Graphical abstract: Editorial Perspectives: 2019 novel coronavirus (SARS-CoV-2): what is its fate in urban water cycle and how can the water research community respond?
Open Access Accepted Manuscript - Highlight

Nano and biosensors for detection of SARS-CoV-2: challenges and opportunities

From the themed collection: 内房股午后迎来上涨
Open Access Perspective

Soft matter science and the COVID-19 pandemic

科学家周日表示,2013年,全球温室气体排放量增加了2.3%,达到历史新高。这个最新迹象表明,在控制全球变暖方面,国际社会的努力仍远远不够。

Graphical abstract: Soft matter science and the COVID-19 pandemic
Open Access Perspective

Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective

"By the end of next year we will be at the point where the unemployment rate is between 5% and 5.5%, and it will truly feel legitimate," Faucher said.

Graphical abstract: Carbon-based antiviral nanomaterials: graphene, C-dots, and fullerenes. A perspective
Perspective

Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic

plat平坦+form形状→形状平的地方→平台,月台
‘The Mindy Project’ It doesn’t matter that Mindy Kaling’s comedy on Fox is in its third season and still not a hit, because it keeps improving with age. It has grown from a one-comedian showcase into a very funny ensemble effort, thanks in part to the addition of Adam Pally in Season 2 and jokes about Ms. Kaling’s alma mater, Dartmouth.
裘德韦伯(Jude Webber)
威廉姆斯指出,据凯投宏观估计,全球经济增长率将从2016年的2.5%上升至今年的2.8%,“新兴世界的大宗商品净出口国的出口额(以美元计算)同比增长应会达到20%左右。”

Graphical abstract: Ultraviolet-C and other methods of decontamination of filtering facepiece N-95 respirators during the COVID-19 pandemic
Perspective

Trends and targets in antiviral phototherapy

激情是保持公司策略顺利运行的关键所在。在创业过程中三心二意,将让你失去成功的动力。从长远来看,坚持不懈是推动一切事物发展的唯一保证,不论是个人生活、工作还是运营一家公司。直到晚年,亚伯拉罕o林肯的大多数努力都以失败告终,但他从未放弃。
The ranking measures the quality and breadth of the schools’ postgraduate programmes. Schools must take part in all four rankings to be eligible for a full score. LBS rose from third last year by participating in all four rankings for the first time.
《请以你的名字呼唤我》
Swyft有50家短信应用合作伙伴,包括Kakao Talk, Facebook Messenger, BlackBerry Messenger和 Line。这种合作让这家只有11个人的小公司能接触到25亿注册用户。随着利用短信应用赚钱的办法不断演化,这家年轻的创业公司已探索出一条可让各大品牌挤进人们聊天领域的生财之道。(财富中文网)

Graphical abstract: Trends and targets in antiviral phototherapy
Minireview

A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays

Although Guo has not given any timetable for her retirement, her announcement at December's East Asian Games about a possible one-year hiatus is a clear enough signal. From all evidence, her relationship with Fok seems to have entered another stage. Unless they truly believe that the Chinese lunar calendar warns against a "widow's year" in 2010, we might well see Miss Guo become Mrs Fok.

Graphical abstract: A new point-of-care test for the diagnosis of infectious diseases based on multiplex lateral flow immunoassays
Minireview

Novel biosensing methodologies for ultrasensitive detection of viruses

At present, 15 Chinese cities allow a 72-hour visa-free entry for nationals of certain countries. Shanghai, Jiangsu and Zhejiang offer 144-hour visa-free stays for international transit passengers from certain countries.

Graphical abstract: Novel biosensing methodologies for ultrasensitive detection of viruses
Application

Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug

2. Google Docs
您只需轻轻一挥将它们放飞,泡沫气球就会自己飘向空中。

Graphical abstract: Anti-tumor, -viral, and -bacterial activities of polyoxometalates for realizing an inorganic drug
Open Access Review Article

ACE2 as a potential therapeutic target for pandemic COVID-19

影片讲述了一个神秘的水生生物和莎莉霍金斯扮演的哑女之间超凡脱俗的爱情故事。
8.《生活大爆炸》白板上的公式都是真的

Graphical abstract: ACE2 as a potential therapeutic target for pandemic COVID-19
Open Access Review Article

Diagnostic technologies for COVID-19: a review

China will remain an important engine for world growth amid sluggish global economic recovery.
Ms Lewis urged people to contact family, neighbours or an animal shelter if they were no longer able to care for their pets.

Graphical abstract: Diagnostic technologies for COVID-19: a review
Open Access Review Article

Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review

'It doesn't have carbs, fat or protein so it won't provide calories, unlike sprinkles which have sugar. It's mostly for decoration. It's tasteless,' said registered dietician Alix Turoff.
A private reading on China's manufacturing sector suggests the slowdown continued last month but that conditions had not worsened as much as in October. The Caixin-sponsored preliminary manufacturing PMI was 48.6 in November, versus expectations of 48.3. It had been 48.3 in October.
卓越雇主排名:12
consistently

Graphical abstract: Targeting severe acute respiratory syndrome-coronavirus (SARS-CoV-1) with structurally diverse inhibitors: a comprehensive review
Open Access Review Article

An overview of key potential therapeutic strategies for combat in the COVID-19 battle

在牵手其他领域的精英这一点上,谷歌并非独家。今年早些时候,英特尔(Intel)便宣布与美国时尚设计师协会(Council of Fashion Designers of America,CFDA)和奢侈品零售商Opening Ceremony合作,设计智能手镯。时尚品牌汤丽柏琦(Tory Burch)也与Fitbit携手设计了与可穿戴技术创业公司Misfit Wearables的无线运动跟踪器Shine Tracker类似的吊坠与手镯。而苹果(Apple)也发掘了各行各业的人才,包括博柏利(Burberry)前任首席执行官安吉拉o阿伦德茨(担任零售主管)、伊夫o圣o洛朗(Yves Saint Laurent)前任首席执行官保罗o丹尼佛以及耐克(Nike)的前任设计主管本o谢弗。

Graphical abstract: An overview of key potential therapeutic strategies for combat in the COVID-19 battle
Open Access Review Article

Potential repurposed SARS-CoV-2 (COVID-19) infection drugs

企业能否最终摆脱谨慎情绪?
不过,在这一反弹中也出现了奖金数额的下滑:去年的平均年终奖是12821元人民币(合1861美元),比2015年多了大约2000元人民币,却仍比2014年的平均值少了800元人民币。在奖金缩水的被调查者中,逾四分之一的人将原因归结为公司业绩太差。

Graphical abstract: Potential repurposed SARS-CoV-2 (COVID-19) infection drugs
Open Access Review Article

Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale

但事实上,作为一项新技术以及新运动,比特币在2014年表现出了猛烈的势头,而且在新的一年有望征服更多怀疑论者。诸多领域的指标证明了这一点:与比特币相关的初创企业和就业岗位数量大增;接受比特币的机构数量也大大增加;开发人员间的活动也较此前增强。

Graphical abstract: Nature as a treasure trove of potential anti-SARS-CoV drug leads: a structural/mechanistic rationale
Review Article

In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections

1q_LRV!0kJXXtQDOIg7_

Graphical abstract: In search for effective and definitive treatment of herpes simplex virus type 1 (HSV-1) infections
Review Article

Antiviral drug discovery: broad-spectrum drugs from nature

We will continue to encourage people to start businesses and make innovations.
The EU’s Americas gambits
Just because the job market is tough doesn't mean it's impossible. "You have to work harder at the job search," Challenger said.
为什么这么说呢?只需想想最高法院对同性婚姻问题做出裁决之后人们越来越强烈的怒火,想想人们围绕堕胎、奥巴马医改、枪支管制、食品券、共和党州长新推的选民压制等问题越来越强烈的怒火,另外还有保守派和茶党顽固不化,力争推翻一切立法并加强财政紧缩。

Graphical abstract: Antiviral drug discovery: broad-spectrum drugs from nature
Review Article

Influenza neuraminidase: A druggable target for natural products

Make sure you've got a good plan for seeing that your children are cared for when you're scheduled to be in class, and when you need to study. It really is possible to raise children while you're going to school. People do it every day.
我们只把精力在应该关注的地方
Subdivided flats smaller than 100 square feet (9 square meters) can rent for $385 in the Asian city.
斯特罗恩表示,他认为IP-BOX运用了和FBI没有经过苹果公司的帮助而破解塞义德·法鲁克iPhone 5c相同的技术。现在FBI已经开始向其他执法部门提供帮助解锁iPhone,iPad或者iPod Touch的方法。苹果方面正在积极寻找FBI是如何破解iPhone的,并将推出软件更新来关闭这些漏洞。
节目37 相声《东西南北大拜年》,赵炎 逗笑 逗乐 大新等

Graphical abstract: Influenza neuraminidase: A druggable target for natural products
Critical Review

Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle

Tracey and Viv Williams, a British couple, dressed as the green cartoon ogres from Shrek at their wedding held recently. Tracy, 33, made a lovely Princess Fion
The ground-breaking discoveries in physics, have ignited a firestorm of research, and it’s only a matter of time before their research leads to advances as unimaginable to us now as lasers and computer chips were a hundred years ago, Laura H. Greene, president-elect of the American Physical Society told The New York Times.

Graphical abstract: Emerging investigators series: the source and fate of pandemic viruses in the urban water cycle
From the themed collection: 北京市将建100家园艺驿站
Critical Review

The role of biosensors in the detection of emerging infectious diseases

全食首席执行官约翰麦基

Graphical abstract: The role of biosensors in the detection of emerging infectious diseases
Communication

Quantitative determination of mechanical stability in the novel coronavirus spike protein

Similar to quick LinkedIn overhauling, Foss says employers will likely notice if you abruptly go from tweeting cat GIFs and "Game of Thrones" spoilers to posting thoughtful, industry-focused content and participating in job-search Twitter chats. These are generally good moves for your job search, but bad ones for keeping it under wraps, so again, take it slow。

Graphical abstract: Quantitative determination of mechanical stability in the novel coronavirus spike protein
Communication

Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations

但是,我们也许终于走到了终点。也许只有在该剧落幕之后,它对成衣秀的影响力才会终结。也许我们对历史无休止的模仿(是的,我们曾模仿70年代的风格以及80年代的大波浪头和高垫肩)才会最终停止。
Spending on medicines in "pharmergingmarkets" will rise more than 50 percent over the next five years, ThePharma Letter said, citing IMS.
不过,黄金比萨早就不是第一种加入了黄金的食物。“马尼拉社交俱乐部”是纽约威廉斯堡一家菲律宾餐厅,今年早些时候,餐厅老板Bj?rn DelaCruz制作了一款昂贵的黄金水晶宇部甜甜圈。
In global health, 2016 will be remembered as the year a little known virus made a major impact. It felt strangely familiar, but this time it wasn't Ebola making headlines around the world, it was Zika - a mosquito-borne virus being linked to a huge spike in the number of babies in Brazil born with brain defects.

Graphical abstract: Interaction of hydroxychloroquine with SARS-CoV2 functional proteins using all-atoms non-equilibrium alchemical simulations
Communication

MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling

Goldie Blox是一家玩具公司,使命是重新定义玩具商店中的“粉红走道”。在科学、技术、工程和数学(STEM)教育和职业领域,男性数量要大大多于女性,大部分女孩往往在八岁前就对这些领域失去了兴趣。Goldie Blox所设计的玩具则通过吸引女孩发展强大的口头及故事讲述能力的方式——同时仍提供机会来发展日后可转化成对工程学兴趣的技能——来鼓励和启发未来的工程师们。说到机会,一家玩具初创企业如何能在和一开始就统治着玩具行业的大公司的抗衡中脱颖而出呢?Goldie Blox走出了明智的一步:最近,该公司发布了一段视频,采用了Beastie Boys的歌曲《女孩们》(Girls)做背景音乐,该视频得到了病毒式传播。尽管这段视频最终被撤下,但Goldie Blox在提高公众对让更多女性和女孩对STEM产生兴趣——以及对Goldie Blox玩具——的认知上,做了一份相当不错的工作。
“我首要的使命、首要的责任是忠实于这本书的原始感觉,忠实于伊恩·弗莱明:他的作品、他的世界和他的构想。
['deziɡ,neitid]
在排名靠前的学校中,英国华威商学院(Warwick Business School)排名提升最大,从第16位提升至第9名。整体而言,上海交通大学(Shanghai JiaoTong University)的上海高级金融学院(Shanghai Advanced Institute of Finance)排名提升最大,从第28位提升至第14位。

Graphical abstract: MPLEx: a method for simultaneous pathogen inactivation and extraction of samples for multi-omics profiling
Communication

Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses

President Barack Obama won re-election to a second term in the White House on Tuesday, television networks projected, beating Republican challenger Mitt Romney after a long and bitter campaign。
根据人社部的一份报告显示,雇主们在第一季度通过公共就业服务机构共招募了520万名职工,这一数字同比去年减少了229000人,也就是下降了百分之4.5。

Graphical abstract: Multicolored silver nanoparticles for multiplexed disease diagnostics: distinguishing dengue, yellow fever, and Ebola viruses
Communication

Inhibition of SARS coronavirus helicase by bismuth complexes

低效的邮件沟通包括很多内容,从不及时回复邮件,到表达不清等问题都包括其中。如果你没有及时回复邮件的好习惯,你可能会错过重要的会议或者是截止日期,造成推迟以及迷惑,被认为是不专业的。
China’s foreign exchange reserves posted their third-largest monthly decline on record last month, central bank data showed yesterday, renewing worries about capital outflows after reserves had appeared to stabilise.
数月前,18岁的安娜·费斯·卡尔森在一张艾丽莎的宣传立板边照了张相,发布到了网上,她立刻变成了网络红人。
科技
更重要的是,这些发明在将来或许还能投入生产,造福人类。

Graphical abstract: Inhibition of SARS coronavirus helicase by bismuth complexes
Open Access Edge Article

Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning

Movie buffs will soon be able to celebrate with a visual feast at the Beijing International Film Festival, where nearly 500 high quality films will be shown.
urban
‘Law & Order: SVU’ This NBC ripped-from-the-soap-opera perils of Olivia (Mariska Hargitay) — psychopath rapist-stalker, tortured love affair, new baby — that took up so much air last season finally died down, and this season, the show’s 16th, the detectives got back to sex crimes à clef, including a Ray Rice-inspired episode about a star sportscaster who was seen on a surveillance camera punching the lights out of his wife.

Graphical abstract: Unveiling the molecular mechanism of SARS-CoV-2 main protease inhibition from 137 crystal structures using algebraic topology and deep learning
Open Access Edge Article

A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers

The data showed that Samsung took the top spot, followed by Apple in second place. Even so, the shipments of the two top tech giants declined respectively by 3 percent and 7 percent, demonstrating decreased global market shares.
问:这次又和青木荣合作了,你的感觉怎样?

Graphical abstract: A serological aptamer-assisted proximity ligation assay for COVID-19 diagnosis and seeking neutralizing aptamers
From the themed collection: 世界各国掀起木制品环保壁垒热
Open Access Edge Article

Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods

The molecular mechanism of the proteolysis reaction catalyzed by SARS-CoV-2 Mpro, one of the enzymes essential for the replication process of the virus responsible for the COVID-19 pandemic, is described using computational QM/MM methods.

Graphical abstract: Revealing the molecular mechanisms of proteolysis of SARS-CoV-2 Mpro by QM/MM computational methods
Open Access Edge Article

Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors

By combining evolutionary and physico-chemical principles, previously unknown druggable Zn-sites in multiple conserved SARS-CoV-2 domains have been identified.

Graphical abstract: Multi-targeting of functional cysteines in multiple conserved SARS-CoV-2 domains by clinically safe Zn-ejectors
Open Access Edge Article

Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir

荷兰合作银行是面向全球农户和农业企业的领先融资机构。
Yet there are similarities between the demagogic elements of the Brexit campaign and the rise of Mr Trump.
adj. 反对的,敌对的 v. 和 ... 起冲突,反抗

Graphical abstract: Computer-generated “synthetic contingency” plans at times of logistics and supply problems: scenarios for hydroxychloroquine and remdesivir
From the themed collection: 买建材提防“伪名牌”
Open Access Edge Article

Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes

除非查尔斯-奥克利成功控诉纽约老板詹姆斯-多兰,尼克斯2016-17赛季唯一的亮点将是克里斯塔普斯-波尔津吉斯在全明星周末斩获技巧挑战赛冠军。
民调显示,荷兰选举将是一场胶着战。吕特所属的中右翼自由民主人民党在大多数民调中位居榜首,但仅领先自由党3个百分点。大多数民调显示很大一部分选民仍未做出决定。
Housing advocates worry that if rezoning is not done carefully, communities could quickly gentrify. “Look at what happened in Williamsburg,” said Harvey Epstein, the director of the community development project at the Urban Justice Center, referring to price escalations. “I don’t know why it wouldn’t happen in East New York or the Bronx or in Flushing.”

Graphical abstract: Engineered unnatural ubiquitin for optimal detection of deubiquitinating enzymes
Accepted Manuscript - Paper

A Digital Protein Microarray for COVID-19 Cytokine Storm Monitoring

From the themed collection: 浙江省出台办法规范“网约房”
Open Access Paper

Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)

Exports to both South Korea and Asean countries fell by about 3 per cent, however, while those to re-exporter Hong Kong dropped by more than 16 per cent.

Graphical abstract: Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)
Paper

A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood

马修?麦康纳(Matthew McConaughey)和贾里德?莱托(Jared Leto) 均凭在剧情片《达拉斯买家俱乐部》(Dallas Buyers Club)中的真实演绎荣获金球奖,该片讲述了一群德克萨斯人向艾滋病病毒发起勇敢抗争的故事。获九次金球奖提名的莱昂纳多?迪卡普里奥(Leonardo DiCaprio)因在《华尔街之狼》(The Wolf of Wall Street)的出色表现第二次摘得最佳男演员桂冠。他在发表获奖感言时感谢了影片导演马丁?斯科塞斯(Martin Scorsese)对他的指导(该片是两人第五次合作),并感谢他“允许自己跟着他拍下了这部电影”。

Graphical abstract: A point-of-care selenium nanoparticle-based test for the combined detection of anti-SARS-CoV-2 IgM and IgG in human serum and blood
Open Access Paper

Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations

3. Piggyback Rider
吊床架

Graphical abstract: Assessing potential inhibitors of SARS-CoV-2 main protease from available drugs using free energy perturbation simulations
Open Access Paper

The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives

威廉姆斯的中长期观点可能比巴韦贾更为悲观。他认为,全球出口增速在25至30年的时间里远高于全球GDP增速,意味着“全球化快速发展已经结束”。换句话说,目前的贸易增长放缓是结构性的,而不是周期性的。
这里有一些散步和骑行的小径可通往其他的湖滨社区以及市中心,骑车去市中心15分钟可达,开车10分钟。附近有步行者艺术中心(Walker Art Center)和几座博物馆。冬天湖上很多人玩冰球和滑冰运动;夏天则流行划独木舟、游泳和钓鱼。
v. 置于城堡中,(棋)移动王车易
在参加《007:大破天幕杀机》巡回宣传的同时,玛尔洛也会拍摄由马立克执导的新电影。

Graphical abstract: The inactivation mechanism of chemical disinfection against SARS-CoV-2: from MD and DFT perspectives
Open Access Paper

Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease

Remedy: The tricky aspect of this regret is that it’s typically rooted in hindsight. Only after you’ve left the job and have moved on to something better, do you start beating yourself up for not making the leap sooner, even if it hadn’t been practical or possible. What you can do is to identify the factors that kept you in your former position as red flags to be aware of in the future and work to line up supports that will allow you to more quickly capitalize on other opportunities as they may present themselves. This could include reviewing and updating your resume with new accomplishments on a monthly or quarterly basis, keeping your LinkedIn account current, building up a contingency fund to allow you to feel less tethered to your current pay check and staying in the loop on industry news and gossip to be aware of where your skills and experience could be of value.
经济运行缓中趋稳、稳中向好;

Graphical abstract: Antiviral agents against COVID-19: structure-based design of specific peptidomimetic inhibitors of SARS-CoV-2 main protease
Open Access Paper

Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro

lace
佳士得珠宝部门的国际高级鉴定师吉恩马克·鲁纳尔称:“这颗钻石完美无瑕,从内到外都绝对纯净。”

Graphical abstract: Pharmacophore-based approaches in the rational repurposing technique for FDA approved drugs targeting SARS-CoV-2 Mpro
Open Access Paper

Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein

Take multiple measures to cut costs.

Graphical abstract: Amino acid interacting network in the receptor-binding domain of SARS-CoV-2 spike protein
Paper

Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide

But pop's wider world also offered a lot of pleasures from artists all over the spectrum, such as the 20th century legends like Blondie and Tori Amos, and upstarts like Dua Lipa and Girl Ray.
“Given the unfavourable reaction to the August depreciation, we think any further depreciation will not take place soon,” said Louis Kuijs, an economist at Oxford Economics based in Hong Kong. “In our view the October trade data keep pressure on [the government] for more domestic easing.”
[praim]
Unlike MBAs, masters in management are targeted at those at the beginning of their career.

Graphical abstract: Greener liquid-phase synthesis and the ACE inhibitory structure–activity relationship of an anti-SARS octapeptide
Open Access Paper

Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses

欧洲专利局局长伯努瓦·巴迪斯戴利表示,中国公司专利申请量的增加,反映出中国加速扩张到欧洲、正成为一个知识型的全球创新型国家的事实。
当小李子上台领取奖杯时,制片人哈维·韦恩斯坦兴奋地拍拍他的背,全场观众起立为他喝彩。

Graphical abstract: Anti-inflammatory, antiallergic and COVID-19 protease inhibitory activities of phytochemicals from the Jordanian hawksbeard: identification, structure–activity relationships, molecular modeling and impact on its folk medicinal uses
Open Access Paper

The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor

7. The 2012 Ig Nobel Physics Prize
无从业资格的司机从事网约车服务将面临1万(折合1500美元)至3万元(折合4500美元)的罚款。
单词deputy 联想记忆:

Graphical abstract: The biomaterial polyphosphate blocks stoichiometric binding of the SARS-CoV-2 S-protein to the cellular ACE2 receptor
From the themed collection: 高尔夫球场违建乱象当休矣
Open Access Paper

Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study

[k?n'gr?tju.leit]
克普克表示,就1994-95年墨西哥汇率危机而言,三个因素都起了作用,当时美联储开始以25、50甚至75个基点(1994年11月)的加息幅度进入紧缩周期。
The requirements come from one of two newly issued regulations over the taxi and online ride-hailing services by China's transportation authority. The regulations will take effect in October and November respectively.

Graphical abstract: Ilimaquinone (marine sponge metabolite) as a novel inhibitor of SARS-CoV-2 key target proteins in comparison with suggested COVID-19 drugs: designing, docking and molecular dynamics simulation study
From the themed collection: 家居企业密集IPO行业或大洗牌
Open Access Paper

Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework

Letizia Battaglia
China has fully complied with UN resolutions on the denuclearization of the Korean Peninsula, and is a staunch supporter of upholding the international nuclear non-proliferation regime.

Graphical abstract: Design and optimization of a subunit vaccine targeting COVID-19 molecular shreds using an immunoinformatics framework
Open Access Paper

Several coumarin derivatives and their Pd(II) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach

Coumarin derivatives and their Pd(II)-complexes have shown a higher binding potential towards SARS-CoV-2 Mpro than chloroquine/cinanserin along with lower toxicity.

Graphical abstract: Several coumarin derivatives and their Pd(ii) complexes as potential inhibitors of the main protease of SARS-CoV-2, an in silico approach
From the themed collection: 前4月全国房地产开发投资2.54万亿
Open Access Paper

Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors

Sesquiterpenes, 8α-anisate-dauc-4-ene-3,9-dione (webiol anisate) (1) and 10α-acetoxy-6α-benzoate-jaeschkeanadiol (2) as well as several analogues (3–12) were root extracted from Ferula vesceritensis.

Graphical abstract: Carotane sesquiterpenes from Ferula vesceritensis: in silico analysis as SARS-CoV-2 binding inhibitors
Open Access Paper

Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins

Design of 2-phenylquinazolin-4(3H)one-trihydroxyphenyl Schiff base conjugates as COVID-19 therapy.

Graphical abstract: Quinazoline-Schiff base conjugates: in silico study and ADMET predictions as multi-target inhibitors of coronavirus (SARS-CoV-2) proteins
Open Access Paper

Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform

As well as dancing, she has her eye on singing and acting - she has already acted in the TV shows Drop Dead Diva and Austin & Ally.
源于:last(adj 最后的)
乔斯的母亲因玛·克萨达在接受《西班牙日报》采访时表示,她的儿子想要给自己的乐队“Los Salerosos”(大意为“冒失鬼”)购买乐器。他在乐队里担任小号手。

Graphical abstract: Automated multiplex nucleic acid tests for rapid detection of SARS-CoV-2, influenza A and B infection with direct reverse-transcription quantitative PCR (dirRT-qPCR) assay in a centrifugal microfluidic platform
From the themed collection: 实施乡村振兴战略意义深远
Open Access Paper

A modular microarray imaging system for highly specific COVID-19 antibody testing

“If you were going to be betting, you would bet its going to be warmer than 2015,” said Mr Karl.
The appointment of Inga Beale to run Lloyds of London and of Mary Barra to run General Motors marked an encouraging end to 2013. Progress for women in the coming year will continue to be too little and too slow, but you should expect to see women in positions of power and influence everywhere. Even Japan is starting to try to get women into work.

Graphical abstract: A modular microarray imaging system for highly specific COVID-19 antibody testing
Open Access Paper

Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms

彭博(Bloomberg)的调查分析此前预计1月份中国CPI应上升1.9%。
In this ranking of 90 European business schools, Insead in France leads the field for full-time and EMBA programmes, while the University of St Gallen in Switzerland is top for MiM. Iese of Spain and IMD of Switzerland were ranked number one for customised and open-enrolment executive education programmes respectively.
inspiring

Graphical abstract: Development of a tablet PC-based portable device for colorimetric determination of assays including COVID-19 and other pathogenic microorganisms
Open Access Paper

Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening

In 2017, his 14th season in the league, LeBron James averaged a career high in assists and rebounds. In the first two months of 2017-18, he's averaging a career high in 3-point percentage, but that's been talked about and dissected; it's been written about extensively.

Graphical abstract: Inhibition of SARS-CoV-2 main protease by phenolic compounds from Manilkara hexandra (Roxb.) Dubard assisted by metabolite profiling and in silico virtual screening
Open Access Paper

Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations

A combination of Autodock Vina and FPL calculations suggested that periandrin V, penimocycline, cis-p-Coumaroylcorosolic acid, glycyrrhizin, and uralsaponin B are able to bind well to SARS-CoV-2 Mpro.

Graphical abstract: Rapid prediction of possible inhibitors for SARS-CoV-2 main protease using docking and FPL simulations
Open Access Paper

Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets

《华胥引》
predecessor

Graphical abstract: Curcumin to inhibit binding of spike glycoprotein to ACE2 receptors: computational modelling, simulations, and ADMET studies to explore curcuminoids against novel SARS-CoV-2 targets
Open Access Paper

A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation

In short, some New Yorkers dislike their neighbors almost as much as they do their landlords. Co-op and condominium boards beware: You do not fare much better.
库什纳回忆道,我当时被他深深折服了。他到新闻集团去见默多克时,我与他有了第一次接触,当时我被一同叫去提提意见。达洛伊西奥在会上描述了他想要实现的远景。他帮助默多克加深了对一些事物的见解。达洛伊西奥在台上的优异表现,加上背后李嘉诚的雄厚财力,为Summly招来了包括艾什顿?库奇(Ashton Kutcher)、小野洋子(Yoko Ono)、史蒂芬?弗莱(Stephen Fry)等许多人的捐赠。

Graphical abstract: A density functional theory study on silver and bis-silver complexes with lighter tetrylene: are silver and bis-silver carbenes candidates for SARS-CoV-2 inhibition? Insight from molecular docking simulation
Open Access Paper

An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19

3′-Hydroxy-4′-methoxy-chroman-7-O-β-D-glucopyranoside 4, together with three known compounds, ferulic acid heptyl ester 1, naringenin 2, and 4,2′,4′-trihydroxy-6′-methoxychalcone-4′-O-β-D-glucopyranoside 3, was isolated from peach fruits.

Graphical abstract: An in silico perception for newly isolated flavonoids from peach fruit as privileged avenue for a countermeasure outbreak of COVID-19
Open Access Paper

Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies

o Outside events can intrude.Consumer Reports, which raved about the Model S, reported a few “quirks” recently that included door handles that failed to activate and a center touch screen that went blank, blocking access to most of the car’s functions. Edmunds.com has had trouble with its Model S too. More reports like that will dent Tesla’s heretofore shining reputation.
But nearly two-thirds (65 percent) of white evangelical Protestants say they think the storms are evidence of the "end times" as predicted by the Bible.

Graphical abstract: Understanding the role of galectin inhibitors as potential candidates for SARS-CoV-2 spike protein: in silico studies
Paper

Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material

而诺贝尔物理学奖则颁给了三位生于英国、目前正在美国工作的科学家,肯定了他们对极端状态下物质的特异属性所做的原子级研究。
No. One way it could play out: after a tentative start involving lots of trading stops, bitcoin futures will slowly begin to attract institutional money. Commodity Futures Trading Commission positioning data will reflect the extraordinary long bias that exists for the product among money managers. As the huge cost of rolling futures positions becomes self-evident, longs will complain ever more loudly about routine divergences around settlement time. Just as a senate hearing is being scheduled to investigate potential manipulation of the market, futures prices will fall below spot, initiating a sell-off.

Graphical abstract: Characterization of a commercially-available, low-pressure UV lamp as a disinfection system for decontamination of common nosocomial pathogens on N95 filtering facepiece respirator (FFR) material
Open Access Paper

A facile assay for rapid detection of COVID-19 antibodies

美国上市交易相比2016年(多年来最疲弱的年份之一)出现起色。根据Dealogic的统计,今年迄今已有112笔IPO得到定价,而去年这个时候只有63笔。发行金额翻了一番多,达到316亿美元。

Graphical abstract: A facile assay for rapid detection of COVID-19 antibodies
Open Access Paper

Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses

2002年,一名4岁的小男孩患有耳聋,但他不愿意戴助听器,因为超级英雄们都不戴。之后,漫威(Marvel)创作了一个戴着助听器的蓝耳侠(Blue Ear)。
位居榜单第三的是史蒂夫·卡瑞尔(Steve Carell)。《卑鄙的我2》(Despicable Me 2)在今年大获成功,斩获票房9.19亿美元。该电影系列累计已取得14亿美元的全球票房,该系列第三部《小黄人》(Minions)也即将上映。卡瑞尔今年还出演了小制作独立影片《迷途知返》(The Way Way Back)和《超级魔术师》(The Incredible Burt Wonderstone)。后一部影片的票房虽未能赚回制作成本,但是我们这里只关注票房收入——该部影片为卡瑞尔2013年的电影票房收入又添2,250万美元。
不要马上接受工作录用
Despite our global economy, only 20 percent of Americans speak another language. Sixty Vocab is aiming to change that with it’s online foreign language game. Based on the premise that 2000 words equals 60 percent of a foreign language, Sixty Vocab is aiming to make learning essential vocabulary fun. The games teach the words most commonly used in conversation and applies time-based discipline — the faster you guess the word, the more rapidly you move on to the next one. Bridging the gap between your high school classes and a pricey foreign language program, Sixty Vocab is offering a unique option for those who want to learn a foreign language during their morning coffee or commute.

Graphical abstract: Potential role of medicinal plants and their constituents in the mitigation of SARS-CoV-2: identifying related therapeutic targets using network pharmacology and molecular docking analyses
Open Access Paper

Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2

“We had to make Steve look like a blue-blooded man of great family wealth,” Mr. Corso said. “There’s a specific look, a definite visual that goes along with that.”

Graphical abstract: Remdesivir-bound and ligand-free simulations reveal the probable mechanism of inhibiting the RNA dependent RNA polymerase of severe acute respiratory syndrome coronavirus 2
Open Access Paper

Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease

单词original 联想记忆:
这造成了一种有待填补的身份认同真空。
在《招魂》一举成功后, 埃德·沃伦和罗琳·沃伦夫妇又推出了其续集《招魂2》。 影片讲述了1977年发生在伦敦的一个真实故事——恩菲德招灵事件。

Graphical abstract: Consensus virtual screening of dark chemical matter and food chemicals uncover potential inhibitors of SARS-CoV-2 main protease
Open Access Paper

Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19

The housing slump has cut demand for iron ore, energy and other commodities. Higher global supplies have exacerbated the gap between supply and demand and pushed raw materials prices lower. This dynamic is not expected to change in the near term despite measures such as the interest rate cut in November.
But if the U.S. can avert that Washington-made crisis, the outlook for workers finding jobs is actually looking pretty good for next year. For one thing, the damage of superstorm Sandy will have to be repaired, meaning jobs in construction and retail. Businesses, meanwhile, which have held off investing and hiring because of uncertainty over the fiscal outlook, might finally open their wallets. That means more jobs, too.[qh]

Graphical abstract: Clinical decision support tool and rapid point-of-care platform for determining disease severity in patients with COVID-19
Paper

Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties

进口价值的增长是在强势美元推高进口商成本的情况下实现的。11月份以人民币计算的进口增长幅度则为同比增长13%,反映了人民币的相对弱势。
长话短说,1772年圣诞节后,Seppenwolde很快就破产了。这场灾难是当时荷兰报纸的头条新闻。它彻底毁了阿姆斯特丹一批商人和银行家。为了防止出现全面的信贷崩溃,阿姆斯特丹市只能作为最后贷款人暂时介入。这种情形是不是似曾相识?

Graphical abstract: Whole-genome sequence analysis and homology modelling of the main protease and non-structural protein 3 of SARS-CoV-2 reveal an aza-peptide and a lead inhibitor with possible antiviral properties
Open Access Paper

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease

Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease.

Graphical abstract: Molecular docking reveals the potential of Salvadora persica flavonoids to inhibit COVID-19 virus main protease
From the themed collection: 大盘反弹 抄底LED照明产业正当时
Paper

Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract

《南华早报》援引当地公安局李剑敏告诉新华社记者的消息:“整个加工车间里又腥又臭,人进去待一两分钟就受不了。”

Graphical abstract: Smartphone-based multiplex 30-minute nucleic acid test of live virus from nasal swab extract
Open Access Paper

Anti-HIV drug repurposing against SARS-CoV-2

8. Flats are allowed on the red carpet – or are they?
9.千万别相信民调
万圣节距离现在没几天了。这意味着,如果你还没有挑选好你的万圣节服装或者装饰,那你应该立刻开始准备了。

Graphical abstract: Anti-HIV drug repurposing against SARS-CoV-2
Paper

Length-scale dependence of protein hydration-shell density

Gitanjali Rao是从10名参加决赛的选手们中被选出来的,他们花了三个月的时间与科学家们进行合作,来实现自己的想法。
她说:“我们一直在寻找他的遗骨,终于找到了。现在是为他恢复名誉的时候了。”
内森是少数几位在夜间拍卖会上积极出价的交易商之一。他在佳士得的拍卖会上代表一位客户以50.65万英镑拍下了查尔斯-安东尼·夸佩尔(Charles-Antoine Coypel)1737年的画作《阿米达宫的毁灭》(The Destruction of the Palace of Armida),售价是预估价的两倍。
“授课的是一流从业者,”该学院一名毕业生表示,“该项目为只有极少金融业工作经验的年轻专业人士量身打造,学生们毕业后马上就能投入工作。”

Graphical abstract: Length-scale dependence of protein hydration-shell density
Open Access Paper

High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus

designer
Some 695 million netizens used mobile phones to access the Internet in 2016, with a growth rate exceeding 10 percent for the third straight year, the report said. Smartphone-based Internet use accounted for 95.1 percent of all Internet users, up from 90.1 percent in 2015.

Graphical abstract: High antiviral activity of mercaptoethane sulfonate functionalized Te/BSA nanostars against arterivirus and coronavirus
From the themed collection: 北京大兴瀛海“限竞房”限价5万5
Paper

A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor

从2015年至2016年,美国ETF市场增长20%,而亚洲市场仅扩大10%。分析师们表示,从两个角度可以看出亚洲ETF市场的规模不及美国和欧洲:后者的市场规模是亚洲的两倍,ETF管理的资产规模为7160亿美元。
“有个人给同事发了条短信说自己辞职了,并请她把这条短信转发给高管。”
当晚的最高价来自唯一的一位欧洲电话出价人。此人以910万英镑购得约翰·康斯特布尔(John Constable)令人钦佩但很难让人喜爱的1824年纵向风景画《水闸》(The Lock)的1825年缩小版,这幅画从1855年起一直由一个英国家族私藏。

Graphical abstract: A handheld continuous-flow real-time fluorescence qPCR system with a PVC microreactor
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In 2011 the owner of the tomb was identified as Liu Fei (169BC-127BC) the first king of Jiangdu an autonomous kingdom within the Han Dynasty according to China News.
The dollar value of China’s exports fell markedly more than expected last month and import growth more than halved, while revisions to November data erased what had appeared to be a long-hoped-for return to growth for outbound shipments.

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